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Jamie Goode A. The Goode Guide to Wine

Jamie Goode A. Development of the Cardiac Conduction System


The pacemaking and conduction system (PCS) is vital for generating and synchronizing the heart beat. Dysfunction of this system can be a direct cause of cardiac conduction disturbance, arrhythmias and sudden cardiac death. A wealth of information has been collected over many years on the unique histological, morphological and phenotypic characteristics of specialized cardiac tissues. The cellular and molecular mechanisms that govern development of the PCS are now starting to be understood. This book draws together contributions from an international and interdisciplinary group of experts working on both basic and clinical aspects of cardiac development. It features reviews of the structure and function of the developing PCS, discussion of the molecular and cellular mechanisms regulating embryological development of this system and studies on the fundamental basis of PCS pathology. The book also considers how novel therapeutic interventions based on understanding of the developmental biology of cardiac pacemaking and conduction tissues might ultimately impact on clinical medicine.

19467.98 RUR

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Jamie Goode A. The Molecular Biology and Pathology of Elastic Tissues


Drawing together contributions from a diverse group of international experts in the field, this collection of papers examines the biology and pathology of elastin at the molecular level. Topics include the structure, ultrastructure and function of elastin; elastin regulation; elastin's role in aging, lung development and disease and atherosclerosis; as well as related aspects of pharmacology and nutrition.

15074.77 RUR

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Jamie Goode A. The hERG Cardiac Potassium Channel


This book draws together contributions from basic, pharmaceutical and clinical sciences aimed at a better understanding of the structure and function of hERG and the molecular basis for compound binding. It features regulatory authority perspectives on preferred preclinical test systems and includes topics on hERG channel gating, regulation of functional expression, pharmacological properties of hERG/IKr channels, drug-induced long QT syndrome and preclinical evaluation and regulatory recommendations for assessing QT prolongation risks. Better understanding of the role of the hERG channel in drug-induced cardiac arrhythmias should ultimately lead to the development of important, new and safer medicines.

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Todd Durham A. Integrated Cardiac Safety


The serious nature of cardiovascular adverse drug reactions occurring in patients makes assessment of a drug's cardiac safety profile a high priority during both development and post-approval monitoring. Integrated Cardiac Safety provides necessary guidance and methodology for professionals assessing cardiac safety of drugs throughout all stages of the drug's life, from discovery and development through postmarketing research. This self-contained, reader-friendly text is valuable to professionals in the pharmaceutical, biotechnology, and CRO industries, pharmacologists, toxicologists, government officials, and students.

9471.26 RUR

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Andro G. Kacharava Pocket Guide to Diagnostic Cardiac Catheterization


The Pocket Guide to Diagnostic Cardiac Catheterization provides general cardiology fellows, nurses, and technicians entering the cardiac catheterization laboratory a practical guide addressing key aspects of left and right heart catheterization, selective coronary angiography, and the utilization of other invasive cardiology procedures for diagnostic purposes.
Written by a team of physicians from Emory University Hospital’s Cardiac Catheterization Laboratories, practical pearls of wisdom about the technical aspects of cardiac catheterization and other invasive cardiology procedures are presented with step-by-step instructions and easy-to-follow illustrations in this quick reference of essential material.
Also included is a chapter with video clips that highlight the role and technical versatility of the multipurpose catheter in cardiac catheterization—a technique developed, taught, and learned over many generations in the cardiac catheterization laboratories at Emory University.

4235.29 RUR

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Melanie Humphreys Nursing the Cardiac Patient


Nursing the Cardiac Patient is a practical guide that addresses the management of cardiac patients across the spectrum of health care settings. It assists nurses in developing a complete understanding of the current evidence-based practice and principles underlying the care and management of the cardiac patient. It combines theoretical and practical components of cardiac care in an accessible and user-friendly format, with case studies and practical examples throughout.

4392.5 RUR

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David Barrett Cardiac Care


Written by experienced clinicians, Cardiac Care: An Introduction for Nurses takes readers step by step through the patient journey, from initial prevention through the critical period to rehabilitation or palliative care. A fundamental resource for all those new to cardiac care, the book provides a basic grounding in the underlying pathophysiology of the disease as well as an understanding of available treatments and provides an accessible update on the latest research and trends in the cardiac specialty. The editors and contributors have years of experience caring for patients with cardiac disorders. Accessible and interesting update on the latest research and trends in the fast-moving specialty of cardiac care. The book has been designed so that the reader can ‘dip in’ at any point, to find out about a particular aspect of cardiac care.

6804.46 RUR

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Jamie Goode A. Flawless


A New York Times Best Wine Book of 2018Flawless is the first book of its kind dedicated to exploring the main causes of faults in wine. From cork taint, to volatile acidity, to off-putting aromas and flavors, all wine connoisseurs have encountered unappealing qualities in a disappointing bottle. But are all faults truly bad? Are some even desirable? Jamie Goode brings his authoritative voice to the table once again to demystify the science behind what causes a good bottle to go bad. By exposing the root causes of faults in wine, Flawless challenges us to rethink our assumptions about how wine should taste and how we can understand beauty in a glass.

1793.41 RUR

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Gregory Bock R. Heart Failure


Heart failure is the main cause of death and disability in the industrialized world. There is a major need for novel therapeutics for prevention and reversal of cardiac pathology associated with heart failure and cardiac enlargement. Over recent years, dramatic progress has been made in unravelling the cellular circuitry involved in cardiac failure, as well as in normal cardiac growth, development and apoptosis. This work has revealed new and unexpected therapeutic targets in the heart. In addition, advances in understanding the role of stem cells in cardiac physiology have suggested strategies for cardiac repair and regeneration once thought impossible. This book describes the work of leading investigators studying the basic mechanisms of cardiac growth, function and dysfunction. There are also exciting contributions from researchers developing novel therapeutic strategies for cardiac disease. The unique feature is the discussions amongst the contributors, which always return to the same basic problem: how can new data from biological studies be used to design novel therapies for the treatment of cardiac dysfunction following myocardial infarction, hypertension and other disorders? With its strong emphasis on translational research, this book will appeal to both scientists and clinicians interested in diminishing the impact of the current epidemic of cardiac diseases.

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Jamie Goode A. Authentic Wine


"A great primer. . . . If you're new to the natural/organic/biodynamic wine debates, Authentic Wine is the place to start."—Huffington Post<br /><br />"This is one of the most engaging, thoughtful and enlightening books on contemporary wine. . . . A manifesto for an industry looking to shape its future."—Wine And Spirits<br /><br /><br /><br />Naturalness is a hot topic in the wine world. But what exactly is a «natural wine»? For this pioneering book, best-selling wine writer Jamie Goode teams up with winemaker and Master of Wine Sam Harrop to explore the wide range of issues surrounding authenticity in wine. They begin by emphasizing that wine’s diversity, one of its strengths, is currently under threat from increasingly homogenized commercial wines that lack a sense of place. Drawing on a global array of examples and anecdotes, Goode and Harrop examine complex concepts—terroir, biodynamics, and sustainability—in clear language. They also discuss topics including cultured and wild yeasts, wine «faults,» the carbon footprint of the wine industry, «natural» as a marketing concept, and more. <i>Authentic Wine</i> illuminates a subject of great interest to wine producers, consumers, and anyone wondering where the wine industry is headed.

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Marco Ricci Myocardial Protection


Myocardial protection is regarded as one of the most important, yet also most controversial aspects of cardiac surgery. There has been considerable improvement in myocardial protection strategies over recent years, utilising a variety of new approaches to treat cardiac diseases, and this text is intended to embrace the state of the art in this field. The book summarises the state of knowledge on all aspects of myocardial protection, including the latest in the treatment of cardiac diseases, robotics, pediatric surgery and the treatment of cardiac failure. Robotic surgery, valvular surgery, pediatric surgery and coronary surgery are all covered by renowned experts, producing a comprehensive, forward-looking view of the field of myocardial protection. This book should function to update physicians and surgeons interested in the field of cardiac surgery on the current state of knowledge on myocardial protection.

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Michael Artman Cardiovascular Development and Congenital Malformations


Congenital cardiovascular malformations are the single most common form of birth defect. Therefore a better understanding of the mechanisms involved in both normal cardiac development and the formation of cardiovascular structural defects is of tremendous importance. This book brings together the leading scientists from around the world who are actively engaged in studies of the etiology, morphogenesis and physiology of congenital cardiovascular diseases. A broad variety of approaches, techniques, experimental models and studies of human genetics combine to make this a truly outstanding and unique treatise on this pressing topic. Cardiovascular Development and Congenital Malformations is divided into distinct categories, each focusing on a particular aspect of cardiovascular development. Sections are accompanied by editorial overviews which integrate new findings and place the information into a broader context.

15156.6 RUR

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Berndt Lüderitz, MD Profiles in Cardiac Pacing and Electrophysiology


Profiles in Cardiac Pacing and Electrophysiology is a collection of short biographies of scientists and physicians who have played (or still play) a significant role in improving diagnosis and therapy of heart rhythm disturbances including electrophysiology and pacing. Altogether, approximately 250 remarkable individuals are described. Not only is the book filled with biographies of past pioneers of rhythmology, some of whom lived long ago, but it also includes many contemporary rhythmologists. In addition to these biographies, it contains: An extensive table of the History of the Disorders of Cardiac Rhythm from the 16th to the 20th century A series of historical pages developed by the author for every issue of the Journal of Interventional Cardiac Electrophysiology (JICE) and reflecting eminent personalities or events in medicine A glossary of arrhythmias, electrophysiology and pacing

6973.16 RUR

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Jamie Goode A. Nuclear Organization in Development and Disease


This book draws together contributions from cell and developmental biologists, structural biologists, geneticists and clinical scientists aimed at a better understanding of the cellular and molecular basis of these diseases. Topics include: How nuclear structure and location within a nucleus affect gene expression Chromatin organization and cell differentiation The nature of the interactions between the nuclear envelope and the cytoskeleton The extent to which the cytoskeleton mediates communication between the cell membrane and nucleus in regulating gene expression and whether disruption of such communication might underlie the disease processes It is hoped that a better understanding of the mechanisms leading to disease pathogenesis may ultimately lead to more rational and appropriate treatments.

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Quinn Tom Acute Cardiac Care. A Practical Guide for Nurses


Acute Cardiac Care provides nurses with a comprehensive understanding of the current practice and principles underlying the care and management of acute cardiac conditions. It addresses the management of acute coronary syndromes (ACS) with an emphasis on evidence-based pharmacological management, cardiac emergencies (cardiac arrest, arrhythmia, acute pulmonary oedema, cardiogenic shock), current diagnostic and interventional modalities for the management of ACS, including risk stratification, and the ethical, political, social and economic factors that impact upon the provision of acute cardiac services in Australia and the UK. Edited by renowned academics and clinicians in the field, this practical text will encourage nurses to think critically about evidence and management of acute coronary conditions, and provide a guide on how and where to look for up-to-date evidence and guidelines. KEY FEATURES: A comprehensive and practical guide to the current practice and principles underlying the nursing care of acute cardiac conditions Edited by leading authorities in the field with a wealth of experience in acute cardiac care and resuscitation Has an emphasis on evidence-based practice, encouraging nurses to critically think about their practice Contains learning objectives, key points and activities and further reading guidelines

5340.06 RUR

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Brooks Edwards S. Pathology of Sudden Cardiac Death


Pathology of Sudden Cardiac Death provides a comprehensive review of cardiovascular disorders. While sudden cardiac death could primarily be seen as an arrhythmogenic event, this actually represents the minority of cases. For the vast majority, there is an underlying anatomic disorder of the cardiovascular system responsible for the ultimate hemodynamic collapse known as sudden cardiac death. Although an increasing array of non-invasive diagnostic tools continue to develop, many physicians and operators of these new diagnostic modalities have never actually seen specimens which demonstrate the fundamental pathologic abnormalities. By providing an atlas style review of ischemic and non-ischemic etiologies of sudden cardiac death, this book opens a window to see the underlying pathology first hand.

12313.93 RUR

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Allan Jaffe S. Markers in Cardiology


With the rapid development of the field of cardiac biomarkers comes a need for updated guidance on how to use them clinically. Drs. Adams, Jaffe, and Apple meet that need with this timely reference. Taking a case-oriented approach for the greatest clinical relevance, the book bridges the gap between science and practice. If you use – or want to use – cardiac markers such as BNP and troponin to help your patients, you will find this clear and comprehensive reference provides a dependable source of valuable information. The 19 chapters are divided into three parts: • Cardiac Troponins • Natriuretic Peptides • Contemporary Markers of Risk The authors cover the technical, clinical, and outcome assessments for each marker used in clinical practice. After each case scenario, an extensive discussion explains the clinical decisions and provides valuable context.

12400.07 RUR

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Jamie Goode A. Pathological Pain


This book brings together contributions from key investigators in the area of pathological pain. It covers the molecular basis of receptors and channels involved in nociception, the possible messages that cause neuropathic plasticity, spinal plasticity in neuropathy, plastic changes in opioid systems in neuropathy and opioid tolerance, and plastic changes related to pathological pain.

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George Billman Edward Novel Therapeutic Targets for Antiarrhythmic Drugs


Profiles potential treatment approaches for cardiac arrhythmias Cardiac arrhythmias of ventricular origin are responsible for the deaths of nearly half a million Americans each year while atrial fibrillation accounts for about 2.3 million cases per year, a rate that is projected to increase 2.5 fold over the next half century. Effectively managing these cardiac rhythm disorders remains a major challenge for both caregivers and the pharmaceutical industry. Filling a gap in the current literature, Novel Therapeutic Targets for Antiarrhythmic Drugs presents the latest treatments for cardiac arrhythmias alongside comprehensive presentations of basic cardiac physiology and pharmacology. Written by leading experts in their research areas, this invaluable resource offers both practitioners and researchers a one-stop guide that brings together previously dispersed information. The text consists of four sections: Section One comprehensively reviews basic cardiac electrophysiology, the mechanisms responsible for arrhythmias in the setting of ischemia, and basic pharmacology of antiarrhythmic drugs. Section Two addresses safety pharmacology, including the concept of «repolarization reserve,» safety challenges, and regulatory issues for the development of novel antiarrhythmic drugs. Section Three describes several novel pharmacological targets for antiarrhythmic drugs, including both ion channel and non-ion channel targets. Section Four describes promising non-pharmacological antiarrhythmic interventions including selective cardiac neural disruption or nerve stimulation, aerobic exercise training, and diet (omega-3 fatty acids). Offering an unparalleled look at the current state and future direction of cardiac arrhythmia treatment, Novel Therapeutic Targets for Antiarrhythmic Drugs provides an important resource to advanced students, working researchers, and busy professionals alike.

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